Breast Cancer Drug Side Effects
Urgent medical-dental alert for people who took
ZOMETA ®, FOSAMAX ®, or
AREDIA ®
These drugs
(Zometa, Fosamax, and Aredia)
have been linked to
the catastrophic condition(s)
“DEAD JAW” (Osteonecrosis of the jaw)
&
other severe conditions
If you or a loved one has been taking any of these “Bisphosphonates”
for Breast Cancer, Osteoporosis,
Cancer or Multiple Myeloma &
you have experienced
complications, you must act now!
YOU MAY DESERVE COMPENSATION!
for
breast cancer drug side effects
Contact today the offices of
Powell
Law Firm, L.C.
is the nation's leading law firm
for
litigation regarding Bisphosphonate Complications.
for your free,
confidential case evaluation
at toll-free 888-238-1998
Please state
your name and phone number
And we will
get back with you promptly
or email us
at
info@mpowelllaw.com
www.MPowellLaw.com
Accepting Inquiries from the U.S. and Internationally
Every case is different. No specific results are
implied.
269
South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
|
Aredia, Zometa and Fosamax Breast Cancer Article Links |
| Aredia and Fosamax
and Zometa linked to jawbone death .or bone tumors. But about 10% were osteoporosis patients who had taken an oral bisphosphonate, mainly Fosamax and Aredia. In May, Ruggiero .Breast Cancer.. |
| Aredia, Fosamax
and
Zometa causes Jaw Problems ...given bisphosphonates intravenously. Some patients take oral bisphosphonates, such as Fosamax and Aredia, for osteoporosis. The FDA acknowledges .Breast Cancer.. |
| Fosamax,
Zometa
and Aredia
Linked to Jaw Osteoporisis .Breast Cancer.or Zoledronate/Zoledronic Acid ( Zometa ) therapy for malignancy, but several have occurred after oral treatment with Alendronate ( Fosamax,Aredia ) or Risedronate ... - Xagena.it |
|
Aredia,
Zometa, Fosamax Breast cancer
Side Effects |
|
Zometa,
Fosamax and Aredia
Attorney Information
|
Fosamax ( generic name - Alendronate ),Zometa and Aredia are types of drugs known as bisphosphonates. Recently a link has been found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw ( ONJ ). This important discovery clearly shows that Aredia side effects may include osteonecrosis of the jaw.
The discovery, published in the Journal of Oral and Maxillofacial Surgeons, prompted both the US, Food and Drug Administration ( FDA ) and Novartis, the manufacturer of bisphosphonates used in cancer chemotherapy, to issue a warning to health care professionals on September 24, 2004. The warning letter contained information about bisphosphonates and the risks of osteonecrosis in the jaw.
Bisphosphonates are commonly used in tablet form such as Aredia and Fosamax ( Alendronate Sodium ) to prevent and treat osteoporosis in post-menopausal women. Stronger forms of bisphosphonates are commonly used in the management of advanced cancers that have metastasized to the bone, where the disease often causes bone pain and possibly even fractures. Several cancers can involve or metastasize to the bone, including lung cancer, breast cancer, prostate cancer, multiple myeloma, and others. When bisphosphonates are given in cancer chemotherapy, the drugs are given intravenously, and usually for longer periods of time.If you or a loved one have taken Fosamax,Zometa or Aredia and have been injured as a result of Fosamax or Aredia side effects such as osteonecrosis of the jaw contact today the offices of
Contact today the offices of
Powell Law Firm, L.C.
is the nation's leading law firm
for litigation regarding Bisphosphonate Complications.
for your free, confidential case evaluation
at toll-free 888-238-1998
Please state your name and phone number
And we will get back with you promptly
or email us at
info@mpowelllaw.com
www.MPowellLaw.com
Accepting Inquiries from the U.S. and Internationally
Every case is different. No specific results are
implied.
269
South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
.
.
Osteonecrosis of the Jaw
Osteonecrosis of the jaw ( ONJ ) is a condition in which the bone tissue in the
jaw fails to heal after minor trauma such as a tooth extraction, causing the
bone to be exposed. The exposure can eventually lead to infection and fracture
and may require long-term antibiotic therapy or surgery to remove the dying
bone tissue. Experts say that prevention and early treatment of individuals
using bisphosphonates such as Fosamax or Zometa is extremely important in preserving the
jaw bone. Individuals using Fosomax, Zometa or other bisphosphonates should attempt to
avoid tooth extractions and other major dental work while on the drugs.
Although most cases of osteonecrosis of the jaw related to Fosamax,Aredia or Zometa
side effects
have occured after dental work several cases have been reported to occur
without any prior dental work. If you are currently taking Fosamax or Zometa
you may be
at risk of developing osteonecrosis. If you have been injured by Fosamax,Aredia or
Zometa side
effects you may be entitled to compensation. For more information about your
legal rights contact the offices of
Contact today the offices of
Powell
Law Firm, L.C.
is the nation's leading law firm
for
litigation regarding Bisphosphonate Complications.
for your free,
confidential case evaluation
at toll-free 888-238-1998
Please state
your name and phone number
And we will
get back with you promptly
or email us
at
info@mpowelllaw.com
www.MPowellLaw.com
Accepting Inquiries from the U.S. and Internationally
Every case is different. No specific results are
implied.
269
South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
- What
is Breast cancer
Breast cancer is a type of cancer in which cells in the breast become abnormal and grow and divide uncontrollably.
Normal Cells
Normal cells divide, grow, and die on a
continual, controlled basis. The nucleus of each cell contains genes
made up of DNA that 'tells' that cell what to do and determines its
lifespan. When cells grow uncontrollably, they will eventually form a
mass, also called a tumor. Benign tumors are not cancer, they do not
invade other types of tissue, but they may pose problems depending on
their size and location if they grow large enough to interfere with a
bodily function (such as blood or urine flow) or put too much pressure
on an organ or nerve.
Cancer
Malignant tumors are made up of abnormal cells that are capable of invading nearby tissues.
Cells from the original tumor may also break off and travel via the blood or lymph systems to distant location (metastasize). When these cancer cells grow in another organ, the cancer will still be named for the organ where it began. For example, if breast cancer cells travel to the liver and grow there, that person would have metastisized breast cancer, not liver cancer.
How Cancer Grows
Cancer
cells grow and divide at an abnormally rapid rate, so they need extra
nutrients. Since cells get their requirements supplied by the blood,
malignant tumors build new blood vessels - a process called
angiogenesis. Developing treatments to stop this process (called
anti-angiogenesis) is one promising area of cancer research.
What Causes the Cells To Grow Uncontrollably?
A change or mutation in the genes of a cell changes the way that cells
acts. The mutation may exist at birth from an inherited genetic trait
from a mother or father or it may be spontaneous - a change that occurs
sometime after birth. Inheriting the BRCA1 or BRCA2 gene has been
identified as a factor in raising the risk of developing breast cancer.
When you hear that a substance is carcinogenic, Some substances, such as cigarettes, have been identified as carcinogens, meaning it is capable of causing a spontaneous genetic mutation that can cause a cancer to begin. Most of the causes of cancer, however, remain unknown. Research is ongoing to understand exactly how each each carcingen causes genetic mutation in hopes of then finding a way to block it.
What is an Oncogene?
Researchers have identified two genes that control cell grow and
division. One is called an oncogene, which gives the command to grow
& divide....think of it as the "on" switch. The other is called a
tumor-suppressor gene, which tells the cell to stop growing and
dividing (think of this as the "off" switch). If the oncogene doesn't
stop giving its "on" command or the tumor suppression gene doesn't give
its "off" command, the cell will grow & divide uncontrollably.
Breast Cancer
The majority (over 75%) of breast cancers begin in the (milk) ducts
within the breast; the next most common site is the lobules - the
glandular tissue that makes milk. Most breast cancers are slow-growing
and by the time a lump can be felt, it may have been growing for 5 or
10 years. Early breast cancer usually has no symptoms and the earlier a
tumor is found, the better the chance of survival. For these reasons it
is extremely important for women to be screened regularly by
mammography or ultrasound since they may identify a cancerous tumor
before it can be felt. In addition, if a lump or thickening can be
felt, it is vital to seek a medical evaluation right away.
Zometa, Fosamax, and Aredia Breast Cancer Drug Side Effects News Articles
IMF: Aredia and Zometa and osteonecrosis of the jaws A New Update ...
| ... finding was the apparent occurrence of jaw osteonecrosis in patients taking
bisphosphonates. ... How common is jaw osteonecrosis in myeloma patients? ... www.myeloma.org/main.jsp?type=article& tab_id=1&menu_id=0&id=1259 - 50k - |
ADRAC : bisphosphonates and osteonecrosis of the jaw
ABC News: Novartis(Aredia,Zometa) Sees Jaw Damage in Cancer Drug Patients
... Novartis AG has received 875 reports of jaw problems in patients treated with two cancer drugs, but it ... sign the cases were related to the drugs, Zometa and Aredia. FDA officials urged further study to ...
- abcnews.go.com/Health/wireStory?id=552022
http://www.bethesda.med.navy.mil/careers/postgraduate_dental_school/research/clinical_updates/2005/0... (MICROSOFT WORD)
Osteoporosis Therapy Resources
MedWatch - 2005 Safety Information Alerts
... Report | Contact MedWatch Zometa (zoledronic acid) Aredia ... of osteonecrosis of the jaw (ONJ) observed in cancer patients ... disorders. Mislabeling problems with certain lots of this product ...
- www.fda.gov/medwatch/SAFETY/2005/safety05.htm